擅长领域
临床诊疗
个人简介
教育经历： (1) 2015-09 至 2022-04, 东北大学, 生物医学工程, 博士 2018-10 至2020-10, 隆德大学, 实验医学，博士联合培养 (2) 2011-09 至 2015-06, 黑龙江大学, 生物工程, 学士 博士后工作经历： 2022-07 至2024-07,西湖大学，张鑫实验室，生物化学 科研与学术工作经历（博士后工作经历除外）： 2024-07 至 今, 中国人民解放军第三军医大学, 第二附属医院, 助理研究员 曾使用其他证件信息：无 近五年主持或参加的国家自然科学基金项目/课题：无 近五年主持或参加的其他科研项目/课题（国家自然科学基金项目除外）： 代表性研究成果和学术奖励情况 一、代表性论著 (1) Di Liu, Jian-Jun Guo, Ji-Hui Su, Alexander Svanbergsson, Lin Yuan, Caroline Haikal, Wen Li, Gunnar Gouras and Jia-Yi Li* Differential seeding and propagating efficiency of α-synuclein strains generated in different conditions. Translational neurodegeneration, 2021;10(1):20. (期刊论文) (2) Alexander Svanbergsson, Fredrik Ek, Isak Martinsson, Jordi Rodo, Di Liu, Edoardo Brandi, Caroline Haikal, Laura Torres-Garcia, Wen Li, Gunnar Goura, Roger Olsson, Tomas Björklund, Jia-Yi Li* FRET-based screening identifies p38 MAPK and PKC inhibition as targets for prevention of seeded α-synuclein aggregation . Neurotherapeutics. 2021;18(3):1692-1709. (期刊论文) (3) Edoardo Brandi, Laura Garcia-Torres, Alexander Svanbergsson, Caroline Haikal, Di Liu , Wen Li, Jia-Yi Li* Brain region-specific microglial and astrocytic activation in response to systemic lipopolysaccharides exposure. Frontiers in aging neuroscience,2022;14:910988. (期刊论文) (4) Dong-Yan Song, Lin Yuan, Na Cui, Cong Feng, Lanxia Meng, Xin-He Wang, Man Xiang, Di Liu , Chun Wang, Zhentao Zhang, Jia-Yi Li*, Wen Li* α-Synuclein induces deficiency in clathrin-mediated endocytosis through inhibiting synaptojanin1 expression, Journal of neurochemistry, 167(3), 461–484. (期刊论文) 二、论著之外的代表性研究成果和学术奖励： Di Liu *, Melek Firat Altay*, Caroline Haikal*, Ann-Laure Mahul, Catherine Strand, Wen Li, Janice Holton, Elisabet Englund, Hilal A Lashuel # , Jia-Yi Li # Pathological features recognized by antibodies targeting different epitopes of alpha-synuclein amongα-synucleinopathies Caroline Haikal*, Melek Firat Altay*, Di Liu*, Ann-Laure Mahul, Catherine Strand, Wen Li, Janice Holton, Elisabet Englund, Hilal A Lashuel # , Jia-Yi Li # Different alpha-synuclein conformations in frontal cortex and hippocampus of patient with dementia with Lewy Bodies. *Equal contribution Synuclein Meeting 2019: where we are and where we need to go (2019, Porto, Portugal) （会议收录）
